CHANGES IN PERIPHERAL MITOCHONDRIAL DNA COPY NUMBER IN METFORMIN-TREATED WOMEN WITH POLYCYSTIC OVARY SYNDROME: A LONGITUDINAL STUDY

Changes in peripheral mitochondrial DNA copy number in metformin-treated women with polycystic ovary syndrome: a longitudinal study

Abstract Background Patients with polycystic ovarian syndrome (PCOS) are associated with known alterations in mitochondria DNA copy number (mtDNA-CN).The aim of this study is to study the change in mtDNA-CN in patients with PCOS who were treated with metformin.Methods This is a prospective cohort of patients with PCOS, who received metformin for on

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Deactivation of the dorsal anterior cingulate cortex indicated low postoperative sports levels in presurgical patients with chronic ankle instability

Abstract Background Injury-related fear contributed to disability in chronic ankle instability (CAI), while there still lacked exploration on the browband. appraisal processes of the injury-related stimuli.This study aimed to compare the neural activities of the appraisal processes of sprain-related stimuli between presurgical chronic ankle instabi

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Tonic and phasic transcutaneous auricular vagus nerve stimulation (taVNS) both evoke rapid and transient pupil dilation

Background: Transcutaneous auricular vagus nerve stimulation (tVNS or taVNS) is a non-invasive method of electrical stimulation of the afferent pathway of the vagus nerve, suggested to drive changes in putative physiological markers of noradrenergic activity, including Travel Case pupil dilation.Objective: However, it is unknown whether different t

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